(L.A.) John McFadden, 67, Died in a Hospital

Case Number: 2009-02267

Los Angeles County is reporting the death of a 67-year-old Caucasian male that occurred in a hospital.

The coroner’s office has identified the man as John McFadden.

Manner of Death: Natural

Cause of Death A: Acute and Chronic Recurrent Bronchopneumonia

Cause of Death B: Chronic Lung Disease, Restrictive/Chronic Bronchitis

Cause of Death C: Dysphagia and Esophageal Reflux Disease

Cause of Death D: Severe Mental Retardation (Fragile X Chromosome)

RIP JOHN MCFADDEN (June 29, 1941 – March 28, 2009)

Formal pronouncement of death was made on Saturday at 2:45 a.m.

The genetic disorder Fragile X syndrome, which results from mutations in a gene on the X chromosome, is the most commonly inherited form of developmental and intellectual disability.

FXS is caused by changes in a gene called Fragile X Messenger Ribonucleoprotein 1 (FMR1). FMR1 usually makes a protein called FMRP that is needed for brain development. People who have FXS do not make this protein.